MultiSciences

CatNum

70-EK180

Product Name

Human IFN-gamma ELISA Kit

Customs Name

Human IFN-gamma ELISA Kit

Applicatio

ELISA

Reactivity

Human

Assay Type

Sandwich ELISA

Suitable Sample Type

serum, plasma, cell culture supernates

Format

96-well strip plate

Storage

4 (unopened) standard stored at -20, others stored at 4 (opened)

Shipping Condition

4

Sample Volume

50 l

Sensitivity

0.30 pg/ml

Standard Curve Range

7.81 - 500 pg/ml

Spike Recovery Range

81 % - 110 %

Mean Spike Recovery

0.92

CV of Intra plate

3.2 % - 6.0 %

CV of Inter plate

3.6 % - 4.4 %

Release Date

Components

Iinterferon-gamma (IFN-) is a dimerized soluble cytokine that is the only member of the type II class of interferons. IFN-, or type II interferon, is a cytokine that is critical forinnate and adaptive immunity against viral, some bacterial and protozoal infections. IFN- is an important activator of macrophages and inducer of Class II major histocompatibility complex (MHC) molecule expression. Aberrant IFN- expression is associated with a number of autoinflammatory and autoimmunediseases. The importance of IFN- in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. IFN- is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 Th1 and CD8 cytotoxic T lymphocyte (CTL) effector T cells onceantigen-specific immunity develops.